Article

Srrm234, but not canonical SR and hnRNP proteins drive inclusion of <i>Dscam</i> exon 9 variable exons

2019-03-21

Abstract excerpt

Alternative splicing of pre-mRNA is a major mechanism to diversify protein functionality in metazoans from a limited number of genes. In the Drosophila melanogaster Down Syndrome Cell Adhesion Molecule (Dscam) important for neuronal wiring up to 38,016 isoforms can be generated by mutually exclusive alternative splicing in four clusters of variable exons. However, it is not understood how a specific exon is chose...

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Literature Corpus work: c16c8b70-d72b-570d-afa7-02f8c11e460c
DOI: 10.1101/584003

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