Article

Systemic Treatment with Nicotinamide Riboside is Protective in Three Mouse Models of Retinal Degeneration

2019-12-06

Abstract excerpt

Purpose: The retina is highly metabolically active, suggesting that metabolic dysfunction could underlie many retinal degenerative diseases. Nicotinamide adenine dinucleotide (NAD + ) is a cofactor and a co-substrate in several cellular energetic metabolic pathways. Maintaining NAD + levels may be therapeutic in retinal disease since retinal NAD + levels decline with age and during retinal damage or degeneratio...

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Literature Corpus work: 523555e2-78e7-5bed-9f0c-682933bd2066
DOI: 10.1101/866798

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