Article

The Temporal Progression of Retinal Degeneration and Early-Stage Idebenone Treatment in the Pde6b rd1/rd1 Mouse Model of Retinal Dystrophy

2023-10-30

Abstract excerpt

Photoreceptor cell death, primarily through apoptosis, related to retinal disorders like retinitis pigmentosa (RP), would result in vision loss. The pathological processes and crucial mutant conditions preceding photoreceptor cell demise are not well understood. This study aims to conduct an in-depth examination of early-stage changes in the widely utilized Pde6b rd1/rd1 (rd1) mouse model, which has Pde6b gene mut...

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Literature Corpus work: d78944ea-f6ae-57b4-aed3-ab7fa7063d7e
DOI: 10.21203/rs.3.rs-3486351/v1

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