Article

Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

2021-12-16

Abstract excerpt

<h4>ABSTRACT</h4> Retinitis Pigmentosa (RP) is a wide array of progressive, debilitating visual disorders caused by mutations in a diverse set of genes. In both human patients and mouse models of RP, rod photoreceptor dysfunction leads to loss of night vision, and is followed by secondary cone photoreceptor dysfunction and degeneration, leading to loss of daylight color vision. A strategy to prevent secondary con...

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Literature Corpus work: 39167275-52b3-5086-b8a8-485bdd640dd4
DOI: 10.1101/2021.12.14.472645

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