Article

Nuclear Localization of Argonaute is affected by Cell Density and May Relieve Repression by microRNAs

2023-07-07

Abstract excerpt

<h4>ABSTRACT</h4> Argonaute protein is associated with post-transcriptional control of cytoplasmic gene expression through miRNA-induced silencing complexes (miRISC). Specific cellular and environmental conditions can trigger AGO protein to accumulate in the nucleus. Localization of AGO is central to understanding miRNA action, yet the consequences of AGO being in the nucleus are undefined. We show nuclear enrich...

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Literature Corpus work: 523463c5-3713-54fc-84c6-54c8fec3d26d
DOI: 10.1101/2023.07.07.548119

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