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Article

Ago HITS-CLIP expands microRNA-mRNA interactions in nucleus and cytoplasm of gastric cancer cells

8 Jan 2019

Abstract excerpt

BACKGROUND: Intensive investigations have identified a collection of microRNAs (miRNAs) and their functional machineries in cytoplasm. However, a comprehensive view of miRNAs and mRNAs in cytoplasm and nucleus has not been explored. This study aims to reveal the mechanisms of miRNA-RNA interactions in nucleus and cytoplasm. METHODS: In this study, the miRNAs and their target mRNAs in the Argonaute2 (Ago2) complex...

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PMID: 30621629
DOI: 10.1186/s12885-018-5246-0

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