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Article

A precursor microRNA in a cancer cell nucleus: get me out of here!

Cell cycle (Georgetown, Tex.) - 15 Mar 2011

Melo Sonia A, Esteller Manel

Abstract excerpt

In line with their broad-based effects, microRNAs (miRNAs), small non-coding RNA molecules ~22 nucleotides long that silence target mRNAs, are thought to act as oncogenes or tumor suppressor genes based on their inhibition of tumor-suppressive and oncogenic mRNAs, respectively. We and others previously showed that global downregulation of miRNAs, a common feature of human tumors, is functionally relevant to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21346411
DOI: 10.4161/cc.10.6.15119
PMCID: PMC3100873

Genes

XPO5
DICER1
TARBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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