Cell-type specific transcriptomic signatures of neocortical circuit organization and their relevance to autism

Abstract excerpt

<h4>ABSTRACT</h4> A prevailing challenge in neuroscience is understanding how diverse neuronal cell types select their synaptic partners to form circuits. In the neocortex, major classes of excitatory projection neurons and inhibitory interneurons are conserved across functionally distinct regions. There is evidence these classes form canonical circuit motifs that depend primarily on their identity; however, regi...

Topics

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• High-Throughput Nucleotide Sequencing
• Hypothalamus
• Mesencephalon
• Neuropeptides
• Neurotransmitter Agents
• Rhombencephalon
• Single-Cell Gene Expression Analysis
• Transcriptome

Identifiers and source

Literature Corpus work

053af43c-9675-51e4-a8f5-de64cad5545f

DOI

10.1101/2022.06.14.496156