Networks of neuronal genes affected by common and rare variants in autism spectrum disorders.

Abstract excerpt

Autism spectrum disorders (ASD) are neurodevelopmental disorders with phenotypic and genetic heterogeneity. Recent studies have reported rare and de novo mutations in ASD, but the allelic architecture of ASD remains unclear. To assess the role of common and rare variations in ASD, we constructed a gene co-expression network based on a widespread survey of gene expression in the human brain. We identified modules...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Nerve Net
• Share to Brain Mapping
• Share to Child Development Disorders, Pervasive