FateLimit quantifies the prediction horizon of cell fate

Abstract excerpt

Single-cell technologies have enabled increasingly detailed reconstruction of developmental trajectories, yet a fundamental question remains unresolved: when does future cellular identity become predictable from a cell’s current molecular state? Existing approaches infer lineage relationships, transition probabilities or future transcriptional dynamics, but do not directly quantify the emergence of fate predictabi...

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• Cancer Cells and Metastasis
• Neonatal Respiratory Health Research
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

2e696c64-831f-5170-98c4-c7c0472b0f47

DOI

10.64898/2026.06.22.733672