Article

Functional synapses between small cell lung cancer and glutamatergic neurons

2023-01-20

Abstract excerpt

Small cell lung cancer (SCLC) is a highly aggressive type of lung cancer, characterized by rapid proliferation, early metastatic spread, clinical recurrence and high rate of mortality. Using in vivo insertional mutagenesis screening in conjunction with cross-species genomic and transcriptomic validation, we identified a strong and consistent signal for neuronal, synaptic, and glutamatergic signaling gene sets in...

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Literature Corpus work: 516ab2fc-cead-516b-b475-f308cd7b971c
DOI: 10.1101/2023.01.19.524045

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