Article

Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing

2024-03-22

Abstract excerpt

Glioblastomas are heterogeneous brain tumors, notorious for their invasive behavior and resistance to therapy. Neuron-to-glioma synapses have been identified to promote glioblastoma invasion and proliferation. However, a comprehensive characterization of tumor-connected neurons has been hampered by a lack of technologies. Here, we adapted retrograde tracing with a modified rabies virus system to characterize and m...

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Literature Corpus work: 7a986afe-6986-52c0-9c79-877e3b19b57c
DOI: 10.1101/2024.03.18.585565

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