Article

Aberrant extracellular matrix and cardiac development in models lacking the PR-DUB component ASXL3

2022-07-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Clinical and research based genetic testing has uncovered genes that encode chromatin modifying complex components required for organogenesis. Covalent histone modifications play a key role in establishing transcriptional plasticity during development, required for cell fate specification, and have been implicated as a developmental mechanism that accounts for autism spectru...

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Literature Corpus work: 514abecf-8f24-58b8-a16d-1f267883d5b6
DOI: 10.1101/2022.07.14.500124

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