Article

The Whsc2/NelfA -dependent transcription complex is required for postnatal cardiac development and heart function

2025-10-24

Abstract excerpt

Cardiac malformations and ventricular remodeling due to heart diseases result in compromised cardiac function, eventually leading to heart failure. In this study, we examine the role of cardiac Wolf-Hirschhorn Syndrome candidate 2 (Whsc2), also known as Negative elongation factor A (NELFA), one of the genes encoded in the WHS critical region. The Wolf-Hirschhorn Syndrome is a contiguous genetic disorder due to mi...

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Literature Corpus work: 7cade369-9026-5743-9cb6-b46b290ef4b0
DOI: 10.1101/2025.10.24.684384

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