Article

Single-Cell RNA-Seq Reveals Endocardial Defect in Hypoplastic Left Heart Syndrome

2019-10-17

Abstract excerpt

<h4>Summary</h4> Hypoplastic left heart syndrome (HLHS) is one of the most challenging forms of congenital heart diseases. Previous studies were mainly focused on intrinsic defects in myocardium. However, this does not sufficiently explain the abnormal development of the cardiac valve, septum, and vasculature, known to originate from the endocardium. Here, using single-cell RNA profiling, induced pluripotent stem...

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Literature Corpus work: abc7274e-f463-5c9a-8825-cf627e7832da
DOI: 10.1101/809731

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