Article

Developmental mis-specification of cardiac conduction and structure transcriptome in Brugada syndrome

2026-07-22

Abstract excerpt

<h4>Background and Aims</h4> Brugada syndrome (BrS) is an inherited arrhythmia associated with ventricular fibrillation and sudden cardiac death. While pathogenic SCN5A variants account for approximately 20-25% of cases, most patients have no identifiable causal rare variant. Genome-wide association studies have identified common susceptibility variants near transcription factor genes involved in cardiac develop...

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Literature Corpus work: 11be723b-6873-5b08-84c9-55e71c9fe0f0
DOI: 10.64898/2026.07.20.26358469

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