Article

The R-loop Grammar predicts R-loop formation under different topological constraints

2024-12-06

Abstract excerpt

R-loops are transient three-stranded nucleic acids that form during transcription when the nascent RNA hybridizes with the template DNA, freeing the DNA non-template strand. There is growing evidence that R-loops play important roles in physiological processes such as control of gene expression, and that they contribute to chromosomal instability and disease. It is known that R-loop formation is influenced by both...

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Literature Corpus work: 50dbd388-5b43-545e-a1c1-e9e52b8d9a8e
DOI: 10.1101/2024.12.03.626533

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