Article

Efficient exploration of sequence space enables rapid generation of functional genome editors

2026-08-17

Abstract excerpt

<h4>ABSTRACT</h4> The problem of how protein sequences translate into defined functions remains largely unsolved despite decades of progress. New methods to efficiently explore protein sequence space will help to shed light on these sequence-function relationships, particularly for complex protein function. Here, we describe an approach to create novel, functional proteins through the integration of deep mutation...

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Literature Corpus work: 2984ec5d-2830-5ec0-9153-07231d000992
DOI: 10.64898/2026.08.16.745112

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