Article

Mathematical Model of a Personalized Neoantigen Cancer Vaccine and the Human Immune System: Evaluation of Efficacy

2021-01-09

Abstract excerpt

Cancer vaccines are an important component of the cancer immunotherapy toolkit enhancing immune response to malignant cells by activating CD4 + and CD8 + T cells. Multiple successful clinical applications of cancer vaccines have shown good safety and efficacy. Despite the notable progress, significant challenges remain in obtaining consistent immune responses across heterogeneous patient populations, as well as...

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Literature Corpus work: b227b1ea-ef0e-5441-9ec1-87f8e4e116e0
DOI: 10.1101/2021.01.08.21249452

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