Back to search

Article

Transcription factor co-binding patterns drive conserved regulatory outcomes

2017-09-15

Abstract excerpt

<h4>ABSTRACT</h4> The mouse has been widely used as a model system in which to study human genetic mechanisms. However, part of the difficulty in translating findings from mouse is that, despite high levels of gene conservation, regulatory control networks between human and mouse have been extensively rewired. To understand common themes of regulatory control we look beyond physical sharing of regulatory sequence...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
507bb8fe-21da-571c-bf0f-3e89826dba39
DOI
10.1101/189571
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transcription factor co-binding patterns drive conserved regulatory outcomesDOI 10.1101/189571
Select a neighboring publication to make it the new centre.