Article
Cross-species regulatory sequence activity prediction.
PLoS computational biology - 1 Jul 2020
Kelley David R
Abstract excerpt
Machine learning algorithms trained to predict the regulatory activity of nucleic acid sequences have revealed principles of gene regulation and guided genetic variation analysis. While the human genome has been extensively annotated and studied, model organisms have been less explored. Model organism genomes offer both additional training sequences and unique annotations describing tissue and cell states...
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