Article

Chronic hypoxia favours adoption to a castration-resistant cell state in prostate cancer

2022-06-29

Abstract excerpt

Predicting and treating recurrence in intermediate-risk prostate cancer patients remains a challenge despite having identified genomic instability (1) and hypoxia (2,3) as risk factors. This underlies challenges in assigning the functional impact of these risk factors to mechanisms promoting prostate cancer progression. Here we show chronic hypoxia (CH), as observed in prostate tumours (4), leads to the adoption o...

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Identifiers and source

Literature Corpus work: 506e9087-9196-5657-9769-4f1ec40bd8ea
DOI: 10.21203/rs.3.rs-1758175/v1

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