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Article

Bad neighbours: hypoxia and genomic instability in prostate cancer

18 Jun 2020

Abstract excerpt

Prostate cancer (PCa) is a clinically heterogeneous disease and has poor patient outcome when tumours progress to castration-resistant and metastatic states. Understanding the mechanistic basis for transition to late stage aggressive disease is vital for both assigning patient risk status in the localised setting and also identifying novel treatment strategies to prevent progression. Subregions of intratumoral...

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Share to Cancer Genomics and Diagnostics
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PMID: 32551913
DOI: 10.1259/bjr.20200087

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