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Article

Subtype and Site Specific–Induced Metabolic Vulnerabilities in Prostate Cancer

16 Sept 2022

Abstract excerpt

Aberrant metabolic functions play a crucial role in prostate cancer progression and lethality. Currently, limited knowledge is available on subtype-specific metabolic features and their implications for treatment. We therefore investigated the metabolic determinants of the two major subtypes of castration-resistant prostate cancer [androgen receptor-expressing prostate cancer (ARPC) and aggressive variant...

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PMID: 36112348
DOI: 10.1158/1541-7786.mcr-22-0250

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