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Article

Role of Hippocampal Glutamatergic Synaptic Alterations in Sevoflurane‐Induced Cognitive Dysfunction in Aged Mice

1 Oct 2024

Abstract excerpt

AIMS: Perioperative neurocognitive disorders (PND), including postoperative delirium (POD) and postoperative cognitive dysfunction (POCD), are common following anesthesia and surgery in older patients and significantly increase morbidity and mortality. However, the underlying mechanism of PND is unclear. Our study aims to analyze the differentially expressed genes (DEGs) in excitatory neurons and investigate the...

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PMID: 39468399
DOI: 10.1111/cns.70093

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