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Depletion of PIEZO1 expression is accompanied by upregulating p53 signaling in mice with perioperative neurocognitive disorder

2023-08-23

Abstract excerpt

As the common complications observed in surgical elder patients, perioperative neurocognitive disorders (PND) cause a series of serious perioperative health problems. However, there are no effective treatments, and the exact mechanisms are still largely unknown. In this study, transcriptome sequencing was performed to investigate the differentially expressed genes (DEGs)in the hippocampus of C57BL/6J aged mice wit...

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Literature Corpus work
59daa184-d67d-5637-96d1-837dd513840f
DOI
10.21203/rs.3.rs-3271772/v1
Open publication

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