Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and epigenetic insights into perioperative neurocognitive disorders: a narrative review.

British journal of anaesthesia - 1 Apr 2026

Thedim Mariana, Li Haobo, Formanek Arthur, Wiener-Kronish Jeanine, Saxena Richa, Vacas Susana

Abstract excerpt

Perioperative neurocognitive disorders (PND) remain a major clinical and public health challenge despite substantial scientific progress over the past two decades. Unidentified traits continue to limit the development of effective pharmacologic strategies and evidence-based care practices, particularly for high-risk patients. Emerging insights into the genetic and epigenetic architecture of PND are revealing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenesis, Genetic
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Neurocognitive Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 41620312
DOI: 10.1016/j.bja.2025.12.046
PMCID: PMC12997105

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and epigenetic insights into perioperative neurocognitive disorders: a narrative review.PMID 41620312Read ↗

Maternal Factors that Induce Epigenetic Changes Contribute to Neurological Disorders in OffspringSemantic proximity Read ↗

Intergenerational Perioperative Neurocognitive DisorderSemantic proximity Read ↗

Genetics and epigenetics in perioperative medicine.Semantic proximity Read ↗

Emerging Role of Long Noncoding RNAs in Perioperative Neurocognitive Disorders and Anesthetic-Induced Developmental NeurotoxicitySemantic proximity Read ↗

The impact of epigenomic next-generation sequencing approaches on our understanding of neuropsychiatric disorders.Semantic proximity Read ↗

Differential DNA Methylation and Delirium After Anesthesia and SurgerySemantic proximity Read ↗

Novel etiological and therapeutic strategies for neurodiseases: epigenetic understanding of gene-environment interactions.Semantic proximity Read ↗

Epigenetics of post-operative delirium: A genome-wide DNA methylation study of neurosurgery patientsSemantic proximity Read ↗

Epigenetic modifications in neuropathic painSemantic proximity Read ↗

Association of Micro RNA and Postoperative Cognitive Dysfunction: A Review.Semantic proximity Read ↗

Excitation-Inhibition Imbalance Underlies Perioperative Neurocognitive Disorders: A Single-Nucleus Transcriptomic Perspective in Mice HippocampusSemantic proximity Read ↗

Glial Contribution to the Pathogenesis of Post-Operative Delirium Revealed by Multi-omic Analysis of Brain Tissue from Neurosurgery PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.