Article
A novel approach to simulate gene-environment interactions in complex diseases.
BMC bioinformatics - 5 Jan 2010
Amato Roberto, Pinelli Michele, D'Andrea Daniel, Miele Gennaro, Nicodemi Mario, Raiconi Giancarlo, Cocozza Sergio
Abstract excerpt
BACKGROUND: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with largest prevalence and mortality (cancer, heart disease, obesity, etc.). Despite a large amount of information that has been collected about both genetic and environmental risk factors, there are few examples of studies on their...
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