Article

Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data

2020-10-23

Abstract excerpt

Over the last decade the availability of SNP-trait associations from genome-wide association studies data has led to an array of methods for performing Mendelian randomization studies using only summary statistics. A common feature of these methods, besides their intuitive simplicity, is the ability to combine data from several sources, incorporate multiple variants and account for biases due to weak instruments a...

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Literature Corpus work: 31fdb6e0-a524-5a39-9e66-87ede4aa38d6
DOI: 10.1101/2020.10.20.20216358

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