Article
Senopathies-Diseases Associated with Cellular Senescence.
Biomolecules - 8 Jun 2023
Lushchak Oleh, Schosserer Markus, Grillari Johannes
Abstract excerpt
Cellular senescence describes a stable cell cycle arrest state with a characteristic phenotype. Senescent cells accumulate in the human body during normal aging, limiting the lifespan and promoting aging-related, but also several non-related, pathologies. We propose to refer to all diseases whose pathogenesis or progression is associated with cellular senescence as "senopathies". Targeting senescent cells with...
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