Article

Shcbp1 deficiency dampens chondrocyte viability and cartilage ECM homeostasis via disturbing coordination of Akt and Erk signal pathways

2023-03-23

Abstract excerpt

<title>Abstract</title> <p>Shcbp1 is known to participate in important signaling pathways related to growth and differentiation, but its role in cartilage has not been well understood. Our previous study found that the expression of Shcbp1 in cartilage is lower in patients with osteoarthritis. Herein, we aim to explore the roles of Shcbp1 and the underlying mechanisms in cartilage development and osteoarthritis p...

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Literature Corpus work: 4eda625d-1853-5400-b15f-ab0d64c436e6
DOI: 10.21203/rs.3.rs-2631935/v1

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