Article

Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and TGFβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis

2024-01-16

Abstract excerpt

<h4>ABSTRACT</h4> As the most common degenerative joint disease, osteoarthritis (OA) contributes significantly to pain and disability during aging. Several genes of interest involved in articular cartilage damage in OA have been identified. However, the direct causes of OA are poorly understood. Evaluating the public human RNA-seq dataset showed that Cbfβ, (subunit of a heterodimeric Cbfβ/Runx1,Runx2, or Runx3 c...

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Literature Corpus work: 6dceca71-89d2-5d49-9da2-12961cec5ca5
DOI: 10.1101/2024.01.15.575763

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