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Article

BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice

19 Mar 2021

Abstract excerpt

destabilization of the medial meniscus (DMM) mouse model to investigate the role of bone morphogenetic protein 5 (BMP5) in osteoarthritis (OA) progression mediated via chondrocyte senescence and apoptosis. BMP5 expression was significantly higher in knee articular cartilage tissues of OA patients and DMM model mice than the corresponding controls. The Osteoarthritis Research Society International scores based on...

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PMID: 33744859
DOI: 10.18632/aging.202708

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