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Article

TAK1 regulates cartilage and joint development via the MAPK and BMP signaling pathways.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Aug 2010

Gunnell Lea M, Jonason Jennifer H, Loiselle Alayna E, Kohn Anat, Schwarz Edward M, Hilton Matthew J, O'Keefe Regis J

Abstract excerpt

The importance of canonical transforming growth factor beta (TGF-beta) and bone morphogenetic protein (BMP) signaling during cartilage and joint development is well established, but the necessity for noncanonical (SMAD-independent) signaling during these processes is largely unknown. TGF-beta act...

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Identifiers

PMID: 20213696
DOI: 10.1002/jbmr.79
PMCID: PMC3153349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20213696-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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