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Article

Analysis of DNA methylation in chondrocytes in rats with knee osteoarthritis

31 Aug 2017

Abstract excerpt

BACKGROUND: Knee osteoarthritis (KOA) is a degenerative knee disease commonly found in the ageing population. DNA methylation works with histone acetylation to participate in aging. Alterations of DNA methylation may involve the joint chondrocyte degeneration in KOA. The aim of this study is to detect DNA methylation changes in chondrocytes of rats with KOA. METHODS: The rat KOA model was established with the...

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PMID: 28859619
DOI: 10.1186/s12891-017-1739-2

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