Article

Secreted spermidine synthase reveals a paracrine role for PGC1α-induced growth suppression in prostate cancer

2024-10-04

Abstract excerpt

<h4>ABSTRACT</h4> Prostate cancer is the fifth cause of death by cancer worldwide, second in incidence in the male population. The definition of the molecular basis of its development and the oncogenic signals driving lethality continue to be important objectives in prostate cancer research. Prior work from others and us has demonstrated that loss of PGC1α expression results in a metabolic, signaling and transcri...

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Literature Corpus work: 4ecde2fc-28bd-5327-a8de-227262336b48
DOI: 10.1101/2024.10.04.614869

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