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Development and validation of a triplex qPCR assay to detect efflux pump-mediated antibiotic resistance in <i>Burkholderia pseudomallei</i>

2018-04-17

Abstract excerpt

<h4>ABSTRACT</h4> Burkholderia pseudomallei , the causative agent of the deadly tropical disease melioidosis, is intrinsically resistant to many antibiotics, leaving few effective treatment options. Trimethoprim-sulfamethoxazole (SXT), meropenem (MEM) and doxycycline (DOX) are valuable antibiotics for melioidosis treatment due to inherently low or no primary resistance. Although considered rare, upregulation of o...

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Literature Corpus work
4eccffc6-3c4c-5ff6-ac6e-5e5effb8c188
DOI
10.1101/301960
Open publication

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