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1-(1-naphthylmethyl)-piperazine inhibition assay successfully rules out efflux pump overexpression in Acinetobacter baumannii

2024-06-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>. Antimicrobial resistance (AMR) in ESKAPE pathogens, notably in carbapenem-resistant <italic>Acinetobacter baumannii,</italic> is a pressing global health concern, contributing to significant AMR-associated mortality. Efflux pump overexpression plays a crucial role in the multidrug resistance (MDR) of <italic>A. baumannii</italic>, but the identification of efflu...

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Literature Corpus work
576dc382-d26a-5f95-b758-03e5c472e51d
DOI
10.21203/rs.3.rs-4504282/v1
Open publication

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