Article

Case Report: Genetic evolution of Burkholderia pseudomallei during treatment leading to antibiotic resistance and disease relapse.

2025-07-30

Abstract excerpt

Background Melioidosis is a significant yet neglected cause of sepsis in tropical regions, particularly in southeast Asia, with poor clinical outcomes. It is a growing threat with an expanding global footprint. The causative organism, Burkholderia pseudomallei , is intrinsically resistant to most first-line empiric antibiotic regimens, but acquired resistance to recommended antibiotics for this infection is uncom...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1a43d243-d164-5793-a176-8813e1fe9141
DOI: 10.12688/wellcomeopenres.24138.2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Case Report: Genetic evolution of Burkholderia pseudomallei during treatment leading to antibiotic resistance and disease relapse.DOI 10.12688/wellcomeopenres.24138.2Read

Case Report: Genetic evolution of Burkholderia pseudomallei during treatment leading to antibiotic resistance and disease relapse – a case report.Semantic proximity Read

Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomalleiSemantic proximity Read

Raising the stakes: Loss of efflux-pump regulation decreases meropenem susceptibility in Burkholderia pseudomalleiSemantic proximity Read

Raising the Stakes: Loss of Efflux Pump Regulation Decreases Meropenem Susceptibility in Burkholderia pseudomallei.Semantic proximity Read

Emergence of ceftazidime resistance in Burkholderia pseudomallei during therapy: Clinical, phenotypic and genotypic insights from paired isolates.Semantic proximity Read

Mechanisms of Antibiotic Resistance in Burkholderia Pseudomallei : Implications for Treatment of MelioidosisSemantic proximity Read

Characterization of ceftazidime resistance mechanisms in clinical isolates of Burkholderia pseudomallei from Australia.Semantic proximity Read

Development of ceftazidime resistance in an acute Burkholderia pseudomallei infectionSemantic proximity Read

Evolution of Burkholderia pseudomallei in Recurrent MelioidosisSemantic proximity Read

Within-host evolution of Burkholderia pseudomallei over a twelve-year chronic carriage infection.Semantic proximity Read

Meropenem resistant Burkholderia pseudomallei - A concerning single case in Australia with no prior meropenem exposureSemantic proximity Read

Phenotypic and genetic alterations of Burkholderia pseudomallei in patients during relapse and persistent infectionsSemantic proximity Read