Article

Tissue-engineered collagenous fibrous cap models to systematically elucidate atherosclerotic plaque rupture

2021-07-20

Abstract excerpt

A significant amount of vascular thrombotic events is associated with rupture of the fibrous cap that overlie atherosclerotic plaques. Cap rupture is however difficult to predict due to the heterogenous composition of the plaque, unknown material properties, and the stochastic nature of the event. Here, we aim to create tissue engineered human fibrous cap models with a variable but controllable collagen compositio...

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Literature Corpus work: 4eac2eab-5a67-57ec-8e77-56358effc33f
DOI: 10.1101/2021.07.20.451997

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