Article

A Sacrificial 3D Printed Vessel-on-Chip Demonstrates a Versatile Approach to Model Connective Tissue Pathology

2025-02-08

Abstract excerpt

For in vitro organ models, perfused vasculature is crucial to overcome nutrient diffusion limits and to generate immunocompetent models by allowing trans-endothelial migration of immune cells in and out of the tissue. However, vasculature is often disregarded due to its complexity to generate and the necessity to integrate flow. The aim here was to overcome these limitations by combining 3D printing and multi-org...

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Literature Corpus work: 6f46c44b-6b23-5d5a-a741-c50e38ff132f
DOI: 10.1101/2025.02.06.636821

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