Article

Investigation into the role of biomechanical forces in determining the behaviour of coronary atherosclerotic plaques

2018-01-01

Abstract excerpt

Ischaemic heart disease remains the single leading cause of death throughout the world. Rupture of an advanced atheromatous coronary plaque precipitates the majority of these clinical events, resulting in thrombosis and myocardial infarction. Post-mortem studies have identified thin-cap fibroatheroma (TCFA) as the plaque subtype most prone to rupture with prospective virtual-histology intravascular ultrasound (VH-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 71b8025d-6e8a-522c-9018-350eba4ce406
DOI: 10.17863/cam.22519

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Investigation into the role of biomechanical forces in determining the behaviour of coronary atherosclerotic plaquesDOI 10.17863/cam.22519Read

Plaque structural stress assessed by virtual histology-intravascular ultrasound predicts dynamic changes in phenotype and composition of untreated coronary artery lesions.Semantic proximity Read

Tissue characterisation of atherosclerotic plaque in the left main: an in vivo intravascular ultrasound radiofrequency data analysis.Semantic proximity Read

Biomechanical factors and macrophages in plaque stability.Semantic proximity Read

Influence of intracoronary hemodynamic forces on atherosclerotic plaque phenotypes.Semantic proximity Read

Combination of plaque burden, wall shear stress, and plaque phenotype has incremental value for prediction of coronary atherosclerotic plaque progression and vulnerability.Semantic proximity Read

Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress.Semantic proximity Read

Low ultimate tensile strain in atherosclerotic plaques is linked to the presence of neovascularisation: insights from <i>ex vivo</i> uniaxial tensile testingSemantic proximity Read

In vivo MRI-based 3D Mechanical Stress–Strain Profiles of Carotid Plaques with Juxtaluminal Plaque Haemorrhage: An Exploratory Study for the Mechanism of Subsequent Cerebrovascular EventsSemantic proximity Read

Global characterization of coronary plaque rupture phenotype using three-vessel intravascular ultrasound radiofrequency data analysis.Semantic proximity Read

Frequency and evolution of thin-capped fibroatheromas in left main coronary artery as assessed by serial virtual histology intravascular ultrasound analysis.Semantic proximity Read

Tissue characterization and phenotype classification in patients presenting with acute myocardial infarction: Insights from the iWonder study.Semantic proximity Read

Coronary atherosclerotic plaque phenotype and physiopathologic mechanisms: Is there an influence of sex? Insights from intracoronary imaging.Semantic proximity Read