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Re-entry into mitosis and regeneration of intestinal stem cells through enteroblast dedifferentiation in <i>Drosophila</i> midguts

2021-11-22

Abstract excerpt

Many adult tissues and organs including the intestine rely on resident stem cells to maintain homeostasis. In mammalian intestines, upon ablation of resident stem cells, the progenies of intestinal stem cells (ISCs) such as secretory cells and tuft cells can dedifferentiate to generate ISCs to drive epithelial regeneration, but whether and how the ISC progenies dedifferentiate to generate ISCs under physiological...

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Identifiers and source

Literature Corpus work
4e8ee83b-9d1e-5424-8ada-379f092d8202
DOI
10.1101/2021.11.22.469515
Open publication

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Re-entry into mitosis and regeneration of intestinal stem cells through enteroblast dedifferentiation in <i>Drosophila</i> midgutsDOI 10.1101/2021.11.22.469515
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