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Article

Tuberous sclerosis complex and Myc coordinate the growth and division of Drosophila intestinal stem cells.

The Journal of cell biology - 16 May 2011

Amcheslavsky Alla, Ito Naoto, Jiang Jin, Ip Y Tony

Abstract excerpt

Intestinal stem cells (ISCs) in the adult Drosophila melanogaster midgut can respond to damage and support repair. We demonstrate in this paper that the tuberous sclerosis complex (TSC) plays a critical role in balancing ISC growth and division. Previous studies have shown that imaginal disc cells that are mutant for TSC have increased rates of growth and division. However, we report in this paper that loss of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21555458
DOI: 10.1083/jcb.201103018
PMCID: PMC3166862

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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