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Article

Lifespan extension by preserving proliferative homeostasis in Drosophila.

PLoS genetics - 14 Oct 2010

Biteau Benoît, Karpac Jason, Supoyo Stephen, Degennaro Matthew, Lehmann Ruth, Jasper Heinrich

Abstract excerpt

Regenerative processes are critical to maintain tissue homeostasis in high-turnover tissues. At the same time, proliferation of stem and progenitor cells has to be carefully controlled to prevent hyper-proliferative diseases. Mechanisms that ensure this balance, thus promoting proliferative homeostasis, are expected to be critical for longevity in metazoans. The intestinal epithelium of Drosophila provides an...

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Identifiers

PMID: 20976250
DOI: 10.1371/journal.pgen.1001159
PMCID: PMC2954830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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