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Article

Drosophila Sulf1 is required for the termination of intestinal stem cell division during regeneration.

Journal of cell science - 15 Jan 2017

Takemura Masahiko, Nakato Hiroshi

Abstract excerpt

Stem cell division is activated to trigger regeneration in response to tissue damage. The molecular mechanisms by which this stem cell mitotic activity is properly repressed at the end of regeneration are poorly understood. Here, we show that a specific modification of heparan sulfate is crucial for regulating Drosophila intestinal stem cell (ISC) division during normal midgut homeostasis and regeneration. Loss...

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Source

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Identifiers

PMID: 27888216
DOI: 10.1242/jcs.195305
PMCID: PMC5278672

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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