Article

Physical cell-cell interactions regulate transcriptional programmes that control the responses of high grade serous ovarian cancer patients to therapy

2024-04-20

Abstract excerpt

<h4>ABSTRACT</h4> The tumour microenvironment is composed of a complex cellular network involving cancer, stromal and immune cells in dynamic interactions. A large proportion of this network relies on direct physical interactions between cells, which may impact patient responses to clinical therapy. Doublets in scRNA-seq are usually excluded from analysis. However, they may represent directly interacting cells. T...

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Literature Corpus work: 4e8dc412-cc9c-5d9d-a994-da405d25c6bb
DOI: 10.1101/2024.04.16.589574

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