Back to search

Article

Neoadjuvant Chemotherapy Modulates the Tumor Microenvironment in High-Grade Serous Ovarian Cancer

2021-04-19

Abstract excerpt

<h4>Background: </h4> While surgical reduction with adjuvant chemotherapy is the traditional treatment for high-grade serous ovarian cancer (HGSOC), neoadjuvant chemotherapy (NACT) has increasingly been applied. This work aims to investigate the expression profiles before and after NACT, explore changes in the tumor microenvironment, expand current treatments, and design a combination of treatment options for pati...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4d5ecff1-5a07-55a7-8259-66f78c9defe7
DOI
10.21203/rs.3.rs-421498/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Neoadjuvant Chemotherapy Modulates the Tumor Microenvironment in High-Grade Serous Ovarian CancerDOI 10.21203/rs.3.rs-421498/v1
The putative effects of carboplatin based neoadjuvant chemotherapy on tumor microenvironment of epithelial ovarian carcinomaSemantic proximity
A Risk Model Based on Tumor Microenvironment to Predict Survival and Immunotherapy Efficacy for Ovarian CancerSemantic proximity
The capacity of the ovarian cancer tumor microenvironment to integrate inflammation signaling conveys a shorter disease-free intervalSemantic proximity
Development and validation of an immune-related prognostic signature for ovarian cancer based on weighted gene co-expression network analysisSemantic proximity
Subtype-specific analysis of gene co-expression networks and immune cell profiling reveals high grade serous ovarian cancer subtype linkage to variable immune microenvironmentSemantic proximity
Development and Validation of an Immune-Related Gene-Pair Model of High-Grade Serous Ovarian Cancer After Platinum-Based ChemotherapySemantic proximity
A Nine-Immune-Related Gene Prognostic Signature for Predicting Outcomes in High-Grade Serous Ovarian CancerSemantic proximity
Identification of a Novel Immune Landscape Signature for Predicting Prognosis and Response of Endometrial Carcinoma to Immunotherapy and ChemotherapySemantic proximity
Identification of Immune-Related Key Genes in Ovarian Cancer Based on WGCNASemantic proximity
Characterizing tumor biology and immune microenvironment in high-grade serous ovarian cancer via single-cell RNA sequencing: insights for targeted and personalized immunotherapy strategiesSemantic proximity
Neoantigens and the tumor microenvironment play important roles in the prognosis of high-grade serous ovarian cancer.Semantic proximity
Comprehensive analysis of prognostic gene signatures based on immune infiltration of ovarian cancerSemantic proximity
Select a neighboring publication to make it the new centre.