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Single-cell sequencing deconvolutes cellular responses to exercise in human skeletal muscle

22 Oct 2022

Abstract excerpt

Skeletal muscle adaptations to exercise have been associated with a range of health-related benefits, but cell type-specific adaptations within the muscle are incompletely understood. Here we use single-cell sequencing to determine the effects of exercise on cellular composition and cell type-specific processes in human skeletal muscle before and after intense exercise. Fifteen clusters originating from six...

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PMID: 36273106
DOI: 10.1038/s42003-022-04088-z

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