Article

Deep Normative Tractometry for Identifying Joint White Matter Macro- and Micro-structural Abnormalities in Alzheimer’s Disease

2024-02-06

Abstract excerpt

This study introduces the Deep Normative Tractometry (DNT) framework, that encodes the joint distribution of both macrostructural and microstructural profiles of the brain white matter tracts through a variational autoencoder (VAE). By training on data from healthy controls, DNT learns the normative distribution of tract data, and can delineate along-tract micro- and macro-structural abnormalities. Leveraging a la...

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Literature Corpus work: a4c4b1ff-a3eb-5397-832d-9539ade6c3aa
DOI: 10.1101/2024.02.05.578943

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